2-Methyl-4-methoxyaniline → 6-Chloro-N-(4-methoxy-2-methyl-phenyl)-nicotinamide

HRID 1201050Notes

Reaction equation

HRID 1201050 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([CH3:10])[c:6]([NH2:7])[cH:8][cH:9]1.[Cl:11][c:12]1[n:13][cH:14][c:15]([C:16](=[O:17])[Cl:18])[cH:19][cH:20]1.[Cl:21][c:22]1[cH:23][cH:24][c:25]([C:26]([NH:27][c:28]2[cH:29][cH:30][c:31]([I:32])[c:33]([CH3:34])[cH:35]2)=[O:36])[cH:37][n:38]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH3:10])[c:6]([NH:7][C:16]([c:15]2[cH:14][n:13][c:12]([Cl:11])[cH:20][cH:19]2)=[O:17])[cH:8][cH:9]1

Participants

4

Reactant 3

HCID 76102-Methyl-4-methoxyanilineHCID 27821656-Chloronicotinoyl ChlorideHCID 593181386-chloro-N-(4-iodo-3-methyl-phenyl)-nicotinamide

Product 1

HCID 98568436-Chloro-N-(4-methoxy-2-methyl-phenyl)-nicotinamide

Sources & evidence

ORD record
ord-a11a21ef8f8f4019ad01c602fb17d044
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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