Methanol → 2-(4-Imidazo[4,5-b]pyridin-3-yl-2-methyl-phenyl)-N-[4-(4-ethyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-acetamide

HRID 1201331Notes

Reaction equation

HRID 1201331 reaction equation
[CH2:21]([CH3:22])[N:23]1[CH2:24][CH2:25][N:26]([CH2:29][c:30]2[c:31]([C:37]([F:38])([F:39])[F:40])[cH:32][c:33]([NH2:36])[cH:34][cH:35]2)[CH2:27][CH2:28]1.[CH3:44][OH:45].[Cl:41][CH2:42][Cl:43].[n:1]1[cH:2][n:3](-[c:10]2[cH:11][c:12]([CH3:20])[c:13]([CH2:16][C:17](=[O:18])[OH:19])[cH:14][cH:15]2)[c:4]2[n:5][cH:6][cH:7][cH:8][c:9]12>>[n:1]1[cH:2][n:3](-[c:10]2[cH:11][c:12]([CH3:20])[c:13]([CH2:16][C:17](=[O:19])[NH:36][c:33]3[cH:32][c:31]([C:37]([F:38])([F:39])[F:40])[c:30]([CH2:29][N:26]4[CH2:25][CH2:24][N:23]([CH2:21][CH3:22])[CH2:28][CH2:27]4)[cH:35][cH:34]3)[cH:14][cH:15]2)[c:4]2[n:5][cH:6][cH:7][cH:8][c:9]12

Participants

5

Reactant 4

HCID 887MethanolHCID 6344DichloromethaneHCID 591345644-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)anilineHCID 67021622HCID 67021622, compound

Product 1

HCID 670236352-(4-Imidazo[4,5-b]pyridin-3-yl-2-methyl-phenyl)-N-[4-(4-ethyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-acetamide

Sources & evidence

ORD record
ord-014493cd42db4a4983f3c0a9e7832703
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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