Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1201374Generated: October 25, 2026

Dimethylformamide → Methyl 4-{6-amino-8-(3-fluorophenyl)-2-[2-(1-hydroxycyclohexyl)-1-ethynyl]-9H-9-purinyl}butanoate

https://huagongshe.com/reaction/1201374

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
Reactant1-EthylcyclohexanolHCID 16021—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactantmethyl 4-[6-amino-8-(3-fluorophenyl)-2-iodo-9H-9-purinyl]butanoateHCID 22133918—
ProductMethyl 4-{6-amino-8-(3-fluorophenyl)-2-[2-(1-hydroxycyclohexyl)-1-ethynyl]-9H-9-purinyl}butanoateHCID 22133832—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-5237b6afbb424bed99e7a3629511cfa2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)