Dimethyl Sulfoxide → trans-N1-(5-chloro-4-(6-fluoropyridin-2-yl)pyrimidin-2-yl)cyclohexane-1,4-diamine
Reaction equation
[CH3:24][S:25]([CH3:26])=[O:27].[CH:16]1([NH2:23])[CH2:17][CH2:18][CH:19]([NH2:22])[CH2:20][CH2:21]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:15])[c:6](-[c:8]2[n:9][c:10]([F:14])[cH:11][cH:12][cH:13]2)[n:7]1>>[c:2]1([NH:22][CH:19]2[CH2:18][CH2:17][CH:16]([NH2:23])[CH2:21][CH2:20]2)[n:3][cH:4][c:5]([Cl:15])[c:6](-[c:8]2[n:9][c:10]([F:14])[cH:11][cH:12][cH:13]2)[n:7]1Participants
4
Sources & evidence
- ORD record
- ord-45eb558a30754833a5a44273eb99840d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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