Water → Tert-butyl 2-((2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinolin-8-yloxy)methyl)morpholine-4-carboxylate

HRID 1201656Notes

Reaction equation

HRID 1201656 reaction equation
[C:26](=[O:27])([O-:28])[O-:29].[CH3:1][O:2][CH2:3][CH2:4][O:5][c:6]1[cH:7][c:8]2[n:9]([cH:10][cH:11]1)[c:12](-[c:15]1[n:16][c:17]3[c:18]([OH:25])[cH:19][cH:20][cH:21][c:22]3[cH:23][cH:24]1)[cH:13][n:14]2.[CH3:32][S:33]([O:34][CH2:37][CH:38]1[O:39][CH2:40][CH2:41][N:42]([C:44](=[O:45])[O:46][C:47]([CH3:48])([CH3:49])[CH3:50])[CH2:43]1)(=[O:35])=[O:36].[Cs+:30].[Cs+:31].[OH2:51]>>[CH3:1][O:2][CH2:3][CH2:4][O:5][c:6]1[cH:7][c:8]2[n:9]([cH:10][cH:11]1)[c:12](-[c:15]1[n:16][c:17]3[c:18]([O:25][CH2:37][CH:38]4[O:39][CH2:40][CH2:41][N:42]([C:44](=[O:45])[O:46][C:47]([CH3:48])([CH3:49])[CH3:50])[CH2:43]4)[cH:19][cH:20][cH:21][c:22]3[cH:23][cH:24]1)[cH:13][n:14]2

Participants

6

Reactant 5

HCID 962WaterHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 57791474Tert-butyl 2-(((methylsulfonyl)oxy)methyl)morpholine-4-carboxylateHCID 66781369HCID 66781369, compound

Product 1

HCID 66781542Tert-butyl 2-((2-(7-(2-methoxyethoxy)imidazo[1,2-a]pyridin-3-yl)quinolin-8-yloxy)methyl)morpholine-4-carboxylate

Sources & evidence

ORD record
ord-3e77a6f34ea640b4b0612f091a0102fa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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