Tert-butyl 4-(4-allyloxyphenyl)-3-hydroxypiperidine-1-carboxylate → tert-Butyl 4-(4-allyloxyphenyl)-3-[1-(3-methoxypropyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-ylmethoxy]piperidine-1-carboxylate

HRID 1201713Notes

Reaction equation

HRID 1201713 reaction equation
[CH2:1]([CH:2]=[CH2:3])[O:4][c:5]1[cH:6][cH:7][c:8]([CH:11]2[CH:12]([OH:24])[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[cH:9][cH:10]1.[Cl:25][CH2:26][c:27]1[cH:28][cH:29][c:30]2[c:35]([cH:36]1)[N:34]([CH2:37][CH2:38][CH2:39][O:40][CH3:41])[C:33](=[O:42])[CH2:32][CH2:31]2>>[CH2:1]([CH:2]=[CH2:3])[O:4][c:5]1[cH:6][cH:7][c:8]([CH:11]2[CH:12]([O:24][CH2:26][c:27]3[cH:28][cH:29][c:30]4[c:35]([cH:36]3)[N:34]([CH2:37][CH2:38][CH2:39][O:40][CH3:41])[C:33](=[O:42])[CH2:32][CH2:31]4)[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[cH:9][cH:10]1

Participants

3

Reactant 2

HCID 54331732Tert-butyl 4-(4-allyloxyphenyl)-3-hydroxypiperidine-1-carboxylateHCID 685044347-chloromethyl-1-(3-methoxypropyl)-3,4-dihydro-1H-quinolin-2-one

Product 1

HCID 68497775tert-Butyl 4-(4-allyloxyphenyl)-3-[1-(3-methoxypropyl)-2-oxo-1,2,3,4-tetrahydroquinolin-7-ylmethoxy]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-633092247661415b95030c7fa3855b50
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…