tert-Butyl 1-oxa-4,9-diazaspiro(5.5)undecane-4-carboxylate → 9-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-1-oxa-4,9-diaza-spiro[5.5]undecane-4-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([O:2][C:3]([N:4]1[CH2:5][CH2:6][C:7]2([O:8][CH2:9][CH2:10][N:11]([CH2:17][c:18]3[cH:19][c:20]4[n:21][c:22]([Cl:33])[n:23][c:24]([N:27]5[CH2:28][CH2:29][O:30][CH2:31][CH2:32]5)[c:25]4[s:26]3)[CH2:12]2)[CH2:13][CH2:14]1)=[O:15])([CH3:16])([CH3:34])[CH3:35].[C:36]([CH3:37])([CH3:38])([CH3:39])[O:40][C:41](=[O:42])[N:43]1[CH2:44][CH2:45][O:46][C:47]2([CH2:48]1)[CH2:49][CH2:50][NH:51][CH2:52][CH2:53]2>>[CH2:17]([c:18]1[cH:19][c:20]2[n:21][c:22]([Cl:33])[n:23][c:24]([N:27]3[CH2:28][CH2:29][O:30][CH2:31][CH2:32]3)[c:25]2[s:26]1)[N:51]1[CH2:50][CH2:49][C:47]2([O:46][CH2:45][CH2:44][N:43]([C:41]([O:40][C:36]([CH3:37])([CH3:38])[CH3:39])=[O:42])[CH2:48]2)[CH2:53][CH2:52]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-57a184abd14d46f9b1f14794dbb0f0b2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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