5-Isocyanatoisoquinoline → N-[3-fluoro-4-(4-methyl-1-piperidinyl)benzyl]-N'-(3-methyl-5-isoquinolinyl)urea
Reaction equation
[F:1][c:2]1[cH:3][c:4]([CH2:5][NH2:6])[cH:7][cH:8][c:9]1[N:10]1[CH2:11][CH2:12][CH:13]([CH3:16])[CH2:14][CH2:15]1.[N:17](=[C:18]=[O:19])[c:20]1[c:21]2[cH:22][c:23]([CH3:30])[n:24][cH:25][c:26]2[cH:27][cH:28][cH:29]1.[N:31]([c:32]1[cH:33][cH:34][cH:35][c:36]2[c:37]1[cH:38][cH:39][n:40][cH:41]2)=[C:42]=[O:43]>>[F:1][c:2]1[cH:3][c:4]([CH2:5][NH:6][C:18]([NH:17][c:20]2[c:21]3[cH:22][c:23]([CH3:30])[n:24][cH:25][c:26]3[cH:27][cH:28][cH:29]2)=[O:19])[cH:7][cH:8][c:9]1[N:10]1[CH2:11][CH2:12][CH:13]([CH3:16])[CH2:14][CH2:15]1Participants
4
Sources & evidence
- ORD record
- ord-216d32db069344e98cbcf0616e031396
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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