Tert-butyl 3-hydroxy-4-{4-[3-(2-methoxybenzyloxy) propoxy]phenyl}piperidine-1-carboxylate → tert-butyl 4-{4-[3-(2-methoxybenzyloxy)propoxy]phenyl}-3-[2-(3-methoxypropyl)-1-(2-trimethylsilanylethoxymethyl)-1H-benzoimidazol-4-ylmethoxy]piperidine-1-carboxylate
Reaction equation
[Cl:35][CH2:36][c:37]1[cH:38][cH:39][cH:40][c:41]2[n:42]([CH2:51][O:52][CH2:53][CH2:54][Si:55]([CH3:56])([CH3:57])[CH3:58])[c:43]([CH2:46][CH2:47][CH2:48][O:49][CH3:50])[n:44][c:45]12.[OH:1][CH:2]1[CH2:3][N:4]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][O:18][CH2:19][c:20]2[c:21]([O:26][CH3:27])[cH:22][cH:23][cH:24][cH:25]2)[cH:12][cH:13]1>>[O:1]([CH:2]1[CH2:3][N:4]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:5][CH2:6][CH:7]1[c:8]1[cH:9][cH:10][c:11]([O:14][CH2:15][CH2:16][CH2:17][O:18][CH2:19][c:20]2[c:21]([O:26][CH3:27])[cH:22][cH:23][cH:24][cH:25]2)[cH:12][cH:13]1)[CH2:36][c:37]1[cH:38][cH:39][cH:40][c:41]2[n:42]([CH2:51][O:52][CH2:53][CH2:54][Si:55]([CH3:56])([CH3:57])[CH3:58])[c:43]([CH2:46][CH2:47][CH2:48][O:49][CH3:50])[n:44][c:45]12Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a90c8d4b842e4d57ba6f4f48a9ab5ee8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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