3-(Trifluoromethyl)benzeneacetic acid → 2-[2-(3-Trifluoromethyl-phenyl)-acetylamino]-pentanoic acid [1-(1,1-dimethyl-2-morpholin-4-yl-ethyl)-1H-imidazol-4-yl]-amide

HRID 1202089Notes

Reaction equation

HRID 1202089 reaction equation
[CH3:1][C:2]([CH2:3][N:4]1[CH2:5][CH2:6][O:7][CH2:8][CH2:9]1)([CH3:10])[n:11]1[cH:12][n:13][c:14]([NH:16][C:17]([CH:18]([CH2:19][CH2:20][CH3:21])[NH2:22])=[O:23])[cH:15]1.[F:24][C:25]([c:26]1[cH:27][c:28]([CH2:32][C:33](=[O:34])[OH:35])[cH:29][cH:30][cH:31]1)([F:36])[F:37]>>[CH3:1][C:2]([CH2:3][N:4]1[CH2:5][CH2:6][O:7][CH2:8][CH2:9]1)([CH3:10])[n:11]1[cH:12][n:13][c:14]([NH:16][C:17]([CH:18]([CH2:19][CH2:20][CH3:21])[NH:22][C:33]([CH2:32][c:28]2[cH:27][c:26]([C:25]([F:24])([F:36])[F:37])[cH:31][cH:30][cH:29]2)=[O:34])=[O:23])[cH:15]1

Participants

3

Reactant 2

HCID 676953-(Trifluoromethyl)benzeneacetic acidHCID 671643342-Amino-pentanoic acid [1-(1,1-dimethyl-2-morpholin-4-yl-ethyl)-1H-imidazol-4-yl]-amide

Product 1

HCID 115190792-[2-(3-Trifluoromethyl-phenyl)-acetylamino]-pentanoic acid [1-(1,1-dimethyl-2-morpholin-4-yl-ethyl)-1H-imidazol-4-yl]-amide

Sources & evidence

ORD record
ord-c6b9885f8570440d82ce8222ec76fa57
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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