Methyl 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate → Methyl 4-(4-fluoro-2-isopropoxyphenylamino)-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate

HRID 1202161Notes

Reaction equation

HRID 1202161 reaction equation
[Cl:13][c:14]1[c:15]2[c:16]([n:17][cH:18][n:19]1)[s:20][c:21]([C:24](=[O:25])[O:26][CH3:27])[c:22]2[CH3:23].[F:1][c:2]1[cH:3][c:4]([O:9][CH:10]([CH3:11])[CH3:12])[c:5]([NH2:6])[cH:7][cH:8]1>>[F:1][c:2]1[cH:3][c:4]([O:9][CH:10]([CH3:11])[CH3:12])[c:5]([NH:6][c:14]2[c:15]3[c:16]([n:17][cH:18][n:19]2)[s:20][c:21]([C:24](=[O:25])[O:26][CH3:27])[c:22]3[CH3:23])[cH:7][cH:8]1

Participants

3

Reactant 2

HCID 2759834Methyl 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylateHCID 37563854-Fluoro-2-(1-methylethoxy)benzenamine

Product 1

HCID 46182043Methyl 4-(4-fluoro-2-isopropoxyphenylamino)-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate

Sources & evidence

ORD record
ord-63b8cd83c9f64adab92ed78ab66a2b4e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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