Acetic Acid → 2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 35

HRID 1202171Notes

Reaction equation

HRID 1202171 reaction equation
[C:24]([OH:25])(=[O:26])[CH3:27].[CH3:1][c:2]1[s:3][c:4](-[c:8]2[n:9][c:10]([NH:14][c:15]3[cH:16][c:17]([N+:21]([O-:22])=[O:23])[cH:18][cH:19][cH:20]3)[n:11][cH:12][cH:13]2)[c:5]([CH3:7])[n:6]1.[CH3:28][O:29][CH2:30][CH2:31][OH:32].[Pd:33]>>[CH3:1][c:2]1[s:3][c:4](-[c:8]2[n:9][c:10]([NH:14][c:15]3[cH:16][c:17]([NH2:21])[cH:18][cH:19][cH:20]3)[n:11][cH:12][cH:13]2)[c:5]([CH3:7])[n:6]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 80192-MethoxyethanolHCID 23938PalladiumHCID 65392934-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(3-nitrophenyl)pyrimidin-2-amine

Product 1

HCID 65393002-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 35

Sources & evidence

ORD record
ord-bfb005f6af8f4858abbbe95f498aa38b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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