tert-Butyl piperazine-1-carboxylate → 4-[7-(2-Butynyl)-1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl]piperazine-1-carboxylic acid tert-butyl ester

HRID 120219Notes

Reaction equation

HRID 120219 reaction equation
[C:19]([CH3:20])([CH3:21])([CH3:22])[O:23][C:24](=[O:25])[N:26]1[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]1.[CH2:1]([C:2]#[C:3][CH3:4])[n:5]1[c:6]([Cl:18])[n:7][c:8]2[n:9]([CH3:17])[c:10](=[O:16])[n:11]([CH3:15])[c:12](=[O:14])[c:13]12>>[CH2:1]([C:2]#[C:3][CH3:4])[n:5]1[c:6]([N:29]2[CH2:28][CH2:27][N:26]([C:24]([O:23][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:25])[CH2:31][CH2:30]2)[n:7][c:8]2[n:9]([CH3:17])[c:10](=[O:16])[n:11]([CH3:15])[c:12](=[O:14])[c:13]12

Participants

3

Reactant 2

HCID 143452tert-Butyl piperazine-1-carboxylateHCID 220294377-(2-Butynyl)-8-chloro-1,3-dimethyl-3,7-dihydropurine-2,6-dione

Product 1

HCID 230819234-[7-(2-Butynyl)-1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl]piperazine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-e6fdc357c49748728a1ea5acb258f057
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…