2-(Tributylstannyl)-1,3-thiazole → N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(thiazol-2-yl)phthalazin-1-amine
Reaction equation
[CH2:34]([Sn:35]([CH2:36][CH2:37][CH2:38][CH3:44])([c:39]1[s:40][cH:41][cH:42][n:43]1)[CH2:45][CH2:46][CH2:47][CH3:48])[CH2:49][CH2:50][CH3:51].[Cl:1][c:2]1[n:3][n:4][c:5]([NH:12][c:13]2[cH:14][cH:15][c:16]([O:19][c:20]3[n:21][cH:22][cH:23][cH:24][c:25]3-[c:26]3[n:27][c:28]([NH:32][CH3:33])[n:29][cH:30][cH:31]3)[cH:17][cH:18]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12.[cH:52]1[cH:53][cH:54][c:55]([P:56]([Pd:57]([P:58]([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)([c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)[c:71]2[cH:72][cH:73][cH:74][cH:75][cH:76]2)([P:77]([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)([c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[c:90]2[cH:91][cH:92][cH:93][cH:94][cH:95]2)[P:96]([c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)([c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)[c:121]2[cH:122][cH:123][cH:124][cH:125][cH:126]2)[cH:127][cH:128]1>>[c:2]1(-[c:39]2[s:40][cH:41][cH:42][n:43]2)[n:3][n:4][c:5]([NH:12][c:13]2[cH:14][cH:15][c:16]([O:19][c:20]3[n:21][cH:22][cH:23][cH:24][c:25]3-[c:26]3[n:27][c:28]([NH:32][CH3:33])[n:29][cH:30][cH:31]3)[cH:17][cH:18]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-93dafab8fdb24029bfd1ed9f26228d59
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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