HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1202299Generated: November 3, 2026
Dichloromethane → 1-(5-Tert-butylisoxazol-3-yl)-3-(3-{7-[1-(2,2-difluoroethyl)piperidin-4-yloxy]-6-methoxyquinazolin-4-yloxy}phenyl)urea
https://huagongshe.com/reaction/1202299
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2,2-Difluoroethyl trifluoromethanesulfonate | HCID 2774089 | — |
| Reactant | 1-(5-Tert-butylisoxazol-3-yl)-3-{3-[6-methoxy-7-(piperidin-4-yloxy)quinazolin-4-yloxy]phenyl}urea | HCID 66875729 | — |
| Product | 1-(5-Tert-butylisoxazol-3-yl)-3-(3-{7-[1-(2,2-difluoroethyl)piperidin-4-yloxy]-6-methoxyquinazolin-4-yloxy}phenyl)urea | HCID 58267918 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
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| ORD ID | ord-9c7a820533f34ee98416b06a73485006 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (5/10) |
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