5-Bromo-2-chloropyridine → tert-butyl 6-(6-chloro-3-pyridinyl)-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridine-1-carboxylate

HRID 1203329Notes

Reaction equation

HRID 1203329 reaction equation
[Br:17][c:18]1[cH:19][cH:20][c:21]([Cl:24])[n:22][cH:23]1.[N:1]1([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH:2]2[CH:3]([CH2:4][CH2:5][CH2:6]1)[CH2:7][NH:8][CH2:9]2>>[N:1]1([C:10](=[O:11])[O:12][C:13]([CH3:14])([CH3:15])[CH3:16])[CH:2]2[CH:3]([CH2:4][CH2:5][CH2:6]1)[CH2:7][N:8]([c:18]1[cH:19][cH:20][c:21]([Cl:24])[n:22][cH:23]1)[CH2:9]2

Participants

3

Reactant 2

HCID 27344145-Bromo-2-chloropyridineHCID 225622021-Boc-octahydropyrrolo(3,4-b)pyridine

Product 1

HCID 22647167tert-butyl 6-(6-chloro-3-pyridinyl)-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b]pyridine-1-carboxylate

Sources & evidence

ORD record
ord-065d3dad49754212a080ba027dba091d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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