2-(Bromomethyl)tetrahydro-2H-pyran → 6-methoxy-1'-(oxolan-2-ylmethyl)spiro[2H-1-benzofuran-3,3'-indole]-2'-one

HRID 1203777Notes

Reaction equation

HRID 1203777 reaction equation
[Br:38][CH2:39][CH:40]1[CH2:41][CH2:42][CH2:43][CH2:44][O:45]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([cH:19][cH:20]1)[C:7]1([CH2:8][O:9]2)[C:10](=[O:18])[NH:11][c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]21.[CH3:21][c:22]1[cH:23][cH:24][c:25]([S:26]([O:27][CH2:32][CH:33]2[O:34][CH2:35][CH2:36][CH2:37]2)(=[O:28])=[O:29])[cH:30][cH:31]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([cH:19][cH:20]1)[C:7]1([CH2:8][O:9]2)[C:10](=[O:18])[N:11]([CH2:32][CH:33]2[O:34][CH2:35][CH2:36][CH2:37]2)[c:12]2[cH:13][cH:14][cH:15][cH:16][c:17]21

Participants

4

Reactant 3

HCID 1419172-(Bromomethyl)tetrahydro-2H-pyranHCID 4522871(Tetrahydrofuran-2-yl)methyl 4-methylbenzenesulfonateHCID 461940466-methoxyspiro[1-benzofuran-3,3'-indol]-2'(1'H)-one

Product 1

HCID 722686426-methoxy-1'-(oxolan-2-ylmethyl)spiro[2H-1-benzofuran-3,3'-indole]-2'-one

Sources & evidence

ORD record
ord-865d255524ab478789b1e3de90ad1ddb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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