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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1204037Generated: November 2, 2026

Dimethyl Sulfoxide → 4-(5-{3-[5-(2-fluoro-1-fluoromethyl-1-methyl-ethyl)-2-p-tolyl-2H-pyrazol-3-yl]-ureido}-6-methyl-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1204037

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantWaterHCID 962—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-Boc-4-(5-amino-6-methyl-2-pyridinyl)piperazineHCID 59134451—
Reactant[5-(2-fluoro-1-fluoromethyl-1-methyl-ethyl)-2-p-tolyl-2H-pyrazol-3-yl]-carbamic acid 2,2,2-trichloro-ethyl esterHCID 68538054—
Product4-(5-{3-[5-(2-fluoro-1-fluoromethyl-1-methyl-ethyl)-2-p-tolyl-2H-pyrazol-3-yl]-ureido}-6-methyl-pyridin-2-yl)-piperazine-1-carboxylic acid tert-butyl esterHCID 68537059—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-e510e5644b394f94ae43c2186eabbab3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)