Methyl 4-(bromomethyl)-3-methoxybenzoate → 4-{3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(2-methyl-pyridin-4-yl)-propyl]-phenoxymethyl}-3-methoxy-benzoic acid methyl ester
Reaction equation
[CH3:24][O:25][C:26]([c:27]1[cH:28][c:29]([O:35][CH3:36])[c:30]([CH2:33][Br:34])[cH:31][cH:32]1)=[O:37].[Cl:1][c:2]1[cH:3][c:4]([OH:23])[cH:5][cH:6][c:7]1[CH:8]([C:9]([C:10]([F:11])([F:12])[F:13])([c:14]1[cH:15][c:16]([CH3:20])[n:17][cH:18][cH:19]1)[OH:21])[CH3:22]>>[Cl:1][c:2]1[cH:3][c:4]([O:23][CH2:33][c:30]2[c:29]([O:35][CH3:36])[cH:28][c:27]([C:26]([O:25][CH3:24])=[O:37])[cH:32][cH:31]2)[cH:5][cH:6][c:7]1[CH:8]([C:9]([C:10]([F:11])([F:12])[F:13])([c:14]1[cH:15][c:16]([CH3:20])[n:17][cH:18][cH:19]1)[OH:21])[CH3:22]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-7f8837052d68400bb2247ef0e5678ff4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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