4-Amino-1-Boc-piperidine → 4-[5-(2-Chloro-pyrimidin-4-yl)-2-methoxy-benzylamino]-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[O:22][C:23](=[O:24])[N:25]1[CH2:26][CH2:27][CH:28]([NH2:31])[CH2:29][CH2:30]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([O:16][CH3:17])[c:12]([CH:13]=[O:14])[cH:15]2)[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([O:16][CH3:17])[c:12]([CH2:13][NH:31][CH:28]3[CH2:27][CH2:26][N:25]([C:23]([O:22][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:24])[CH2:30][CH2:29]3)[cH:15]2)[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-6414998043414ed4b7ea6a197dddc3e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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