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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1204552Generated: November 1, 2026

1,4-Dioxane → (5-Bromo-pyrimidin-2-yl)-(5'-isopropyl-2'-methoxy-4-trifluoromethyl-biphenyl-2-ylmethyl)-amine

https://huagongshe.com/reaction/1204552

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
ReactantDiisopropylethylamineHCID 81531—
Reactant5-Bromo-2-chloropyrimidineHCID 606665—
Reactant1-[5'-Isopropyl-2'-methoxy-4-(trifluoromethyl)biphenyl-2-yl]methanamineHCID 59135127—
Product(5-Bromo-pyrimidin-2-yl)-(5'-isopropyl-2'-methoxy-4-trifluoromethyl-biphenyl-2-ylmethyl)-amineHCID 67087228—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-d241a24b5bd440d2bfb9f911cf553692
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)