Acetic Acid → 1-(5-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-2,2,2-trifluoroethanone

HRID 1204608Notes

Reaction equation

HRID 1204608 reaction equation
[Br:1][c:2]1[c:3]([CH2:4][CH2:5][NH:6][C:7]([C:8]([F:9])([F:10])[F:11])=[O:12])[cH:13][cH:14][cH:15][cH:16]1.[CH3:22][C:23](=[O:24])[OH:25].[S:17](=[O:18])(=[O:19])([OH:20])[OH:21]>>[Br:1][c:2]1[c:3]2[c:13]([cH:14][cH:15][cH:16]1)[CH2:22][N:6]([C:7]([C:8]([F:9])([F:10])[F:11])=[O:12])[CH2:5][CH2:4]2

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 1118Sulfuric AcidHCID 58597272N-[2-(2-bromophenyl)ethyl]-2,2,2-trifluoroacetamide

Product 1

HCID 184142741-(5-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-2,2,2-trifluoroethanone

Sources & evidence

ORD record
ord-c9c188036234412a8a58aada82b2946b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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