4-Oxo-1-phenylcyclohexanenitrile → 3-Bromo-4-oxo-1-phenyl-cyclohexanecarbonitrile

HRID 12049Notes

Reaction equation

HRID 12049 reaction equation
[O:1]=[C:2]1[CH2:7][CH2:6][C:5]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)([C:8]#[N:9])[CH2:4][CH2:3]1.[Br:16]C1CC(C(C)C)CCC1=O>>[Br:16][CH:7]1[C:2](=[O:1])[CH2:3][CH2:4][C:5]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)([C:8]#[N:9])[CH2:6]1

Participants

3

Reactant 2

HCID 912824-Oxo-1-phenylcyclohexanenitrileHCID 627080672-Bromo-4-isopropyl-cyclohexanone

Product 1

HCID 136642703-Bromo-4-oxo-1-phenyl-cyclohexanecarbonitrile

Procedure

The bromination of 4-oxo-1-phenyl-cyclohexanecarbonitrile takes place in a manner similar to that described above for the preparation of 2-bromo-4-isopropyl-cyclohexanone. The title compound is reacted as a crude product without further characterization.

Sources & evidence

ORD record
ord-3a460190a33246fe89fcd72452a31c42
Source dataset
uspto-grants-2010_06
Patent number
US07727979B2

Reaction notes

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