Toluene → (1RS)-4,4,4-Trifluoro-1-(7-methoxyquinolin-3-yl)butan-1-ol
Reaction equation
[Br:6][c:7]1[cH:8][n:9][c:10]2[cH:11][c:12]([O:17][CH3:18])[cH:13][cH:14][c:15]2[cH:16]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[CH3:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[F:19][C:20]([CH2:21][CH2:22][CH:23]=[O:24])([F:25])[F:26]>>[c:7]1([CH:23]([CH2:22][CH2:21][C:20]([F:19])([F:25])[F:26])[OH:24])[cH:8][n:9][c:10]2[cH:11][c:12]([O:17][CH3:18])[cH:13][cH:14][c:15]2[cH:16]1Participants
5
Sources & evidence
- ORD record
- ord-bc66acff76914a6e8fc3279d3bfd6c97
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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