Chloroform → 1-Oxo-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-8-sulfonyl chloride
Reaction equation
[Cl:28][CH:29]([Cl:30])[Cl:31].[F:6][C:7]([O:8][c:9]1[cH:10][cH:11][c:12]([N:15]2[C:16](=[O:25])[C:17]3([CH2:18][CH2:19]2)[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]3)[cH:13][cH:14]1)([F:26])[F:27].[S:1](=[O:2])(=[O:3])([Cl:4])[Cl:5]>>[S:1](=[O:2])(=[O:3])([Cl:5])[N:22]1[CH2:21][CH2:20][C:17]2([C:16](=[O:25])[N:15]([c:12]3[cH:11][cH:10][c:9]([O:8][C:7]([F:6])([F:26])[F:27])[cH:14][cH:13]3)[CH2:19][CH2:18]2)[CH2:24][CH2:23]1Participants
4
Sources & evidence
- ORD record
- ord-e871f1aa819a4eb6931743f90b0f0b37
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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