4-(Trifluoromethyl)phenylboronic acid → 2-Methyl-4-(trifluoromethyl)-1-{[4'-(trifluoromethyl)-3-biphenylyl]methyl}-1H-indole-5-carbonitrile
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:8][n:9]2[c:10]([CH3:24])[cH:11][c:12]3[c:13]([C:20]([F:21])([F:22])[F:23])[c:14]([C:18]#[N:19])[cH:15][cH:16][c:17]23)[cH:5][cH:6][cH:7]1.[F:25][C:26]([c:27]1[cH:28][cH:29][c:30]([B:33]([OH:34])[OH:35])[cH:31][cH:32]1)([F:36])[F:37]>>[c:2]1(-[c:30]2[cH:29][cH:28][c:27]([C:26]([F:25])([F:36])[F:37])[cH:32][cH:31]2)[cH:3][c:4]([CH2:8][n:9]2[c:10]([CH3:24])[cH:11][c:12]3[c:13]([C:20]([F:21])([F:22])[F:23])[c:14]([C:18]#[N:19])[cH:15][cH:16][c:17]23)[cH:5][cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-f08458ce5c2c4680b37a00b3c82662b8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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