1-(5-Phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-amine → 1-(2-Fluoro-4-methoxyphenoxy)-3-(1-(5-phenylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-ylamino)propan-2-ol
Reaction equation
[F:1][c:2]1[c:3]([O:4][CH2:5][CH:6]2[O:7][CH2:8]2)[cH:9][cH:10][c:11]([O:13][CH3:14])[cH:12]1.[c:15]1(-[c:21]2[cH:22][s:23][c:24]3[n:25][cH:26][n:27][c:28]([N:30]4[CH2:31][CH2:32][CH:33]([NH2:36])[CH2:34][CH2:35]4)[c:29]23)[cH:16][cH:17][cH:18][cH:19][cH:20]1>>[F:1][c:2]1[c:3]([O:4][CH2:5][CH:6]([OH:7])[CH2:8][NH:36][CH:33]2[CH2:32][CH2:31][N:30]([c:28]3[n:27][cH:26][n:25][c:24]4[s:23][cH:22][c:21](-[c:15]5[cH:16][cH:17][cH:18][cH:19][cH:20]5)[c:29]43)[CH2:35][CH2:34]2)[cH:9][cH:10][c:11]([O:13][CH3:14])[cH:12]1Participants
3
Sources & evidence
- ORD record
- ord-eb301232428d4727809e2ac89ef9b6b4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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