2,2,2-Trifluoro-1-(pyridin-2-yl)ethan-1-amine → 5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (2,2,2-trifluoro-1-pyridin-2-yl-ethyl)-amide

HRID 1205692Notes

Reaction equation

HRID 1205692 reaction equation
[CH:1]1([c:4]2[cH:5][cH:6][c:7]([C:16](=[O:17])[OH:18])[n:8][c:9]2[O:10][CH2:11][C:12]([F:13])([F:14])[F:15])[CH2:2][CH2:3]1.[F:19][C:20]([CH:21]([NH2:22])[c:23]1[n:24][cH:25][cH:26][cH:27][cH:28]1)([F:29])[F:30]>>[CH:1]1([c:4]2[cH:5][cH:6][c:7]([C:16](=[O:18])[NH:22][CH:21]([C:20]([F:19])([F:29])[F:30])[c:23]3[n:24][cH:25][cH:26][cH:27][cH:28]3)[n:8][c:9]2[O:10][CH2:11][C:12]([F:13])([F:14])[F:15])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 252199112,2,2-Trifluoro-1-(pyridin-2-yl)ethan-1-amineHCID 710876495-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid

Product 1

HCID 866747905-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (2,2,2-trifluoro-1-pyridin-2-yl-ethyl)-amide

Sources & evidence

ORD record
ord-59119714fec440f3b6b73d245e7656b8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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