2-Tert-butyl-4-phenyl-cyclohexanone → 2-Tert-butyl-6-chloro-4-phenyl-cyclohexanone
Reaction equation
[C:1]([CH:5]1[CH2:10][CH:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:8][CH2:7][C:6]1=[O:17])([CH3:4])([CH3:3])[CH3:2].C(C1CCCC([Cl:28])C1=O)(C)(C)C>>[C:1]([CH:5]1[CH2:10][CH:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:8][CH:7]([Cl:28])[C:6]1=[O:17])([CH3:4])([CH3:2])[CH3:3]Participants
3
Procedure
The chlorination of 2-tert-butyl-4-phenyl-cyclohexanone takes place in a manner similar to that described above for the preparation of 2-tert-butyl-6-chloro-cyclohexanone. The title compound is reacted as a crude product without further characterization.
Sources & evidence
- ORD record
- ord-fc11e317df934ddb9fb4ad798f7add3e
- Source dataset
- uspto-grants-2010_06
- Patent number
- US07727979B2
Reaction notes
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