1-[5-(o-chlorophenyl)2,3-dihydro-1-isopropyl-3,3-dimethyl-2-oxo-1H-1,4-benzodiazepin-7-yl]-3-(2-hydroxyethyl)urea → 7-amino-5-(o-chlorophenyl)-1,3-dihydro-1-isopropyl-3,3-dimethyl-2H-1,4-benzodiazepin-2-one
Reaction equation
[Cl:1][c:2]1[c:3]([C:8]2=[N:9][C:10]([CH3:26])([CH3:27])[C:11](=[O:25])[N:12]([CH:22]([CH3:23])[CH3:24])[c:13]3[c:14]2[cH:15][c:16]([N:19]=[C:20]=[O:21])[cH:17][cH:18]3)[cH:4][cH:5][cH:6][cH:7]1.[Cl:28][c:29]1[cH:30][cH:31][cH:32][cH:33][c:34]1[C:35]1=[N:58][C:55]([CH3:56])([CH3:57])[C:53](=[O:54])[N:49]([CH:50]([CH3:51])[CH3:52])[c:48]2[c:36]1[cH:37][c:38]([NH:39][C:40]([NH:41][CH2:42][CH2:43][OH:44])=[O:45])[cH:46][cH:47]2>>[Cl:1][c:2]1[c:3]([C:8]2=[N:9][C:10]([CH3:26])([CH3:27])[C:11](=[O:25])[N:12]([CH:22]([CH3:23])[CH3:24])[c:13]3[c:14]2[cH:15][c:16]([NH2:19])[cH:17][cH:18]3)[cH:4][cH:5][cH:6][cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5fb8e3ebfc034d1385ba61d7e99bfa83
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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