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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 120580Generated: October 27, 2026

Dimethylformamide → 2-aminochloro-N-(5-phenoxy-thiophen-2-ylmethyl)-nicotinamide

https://huagongshe.com/reaction/120580

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantHexafluorophosphateHCID 9886—
ReactantBenzotriazol-1-yloxy-tris(dimethylamino)phosphoniumHCID 124335—
Reactant2-Amino-6-chloronicotinic acidHCID 12263992—
ReactantC-(5-Phenoxy thiophen-2-yl)methylamineHCID 23130515—
Product2-aminochloro-N-(5-phenoxy-thiophen-2-ylmethyl)-nicotinamideHCID 23130498—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-585cbd5a88504a6ba01cbbb6a01a79af
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)