4-(2-Propyn-1-yl)morpholine → {4-[3-Cyclopropylmethoxy-5-(3-morpholin-4-yl-prop-1-ynyl)-phenylsulfanyl]-2-methyl-phenoxy}-acetic Acid Ethyl Ester

HRID 1205936Notes

Reaction equation

HRID 1205936 reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][O:6][c:7]1[c:8]([CH3:26])[cH:9][c:10]([S:13][c:14]2[cH:15][c:16]([Br:25])[cH:17][c:18]([O:20][CH2:21][CH:22]3[CH2:23][CH2:24]3)[cH:19]2)[cH:11][cH:12]1)=[O:27].[CH2:28]([C:29]#[CH:30])[N:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1.[CH2:37]([O:38][C:39](=[O:40])[CH2:41][O:42][c:43]1[cH:44][cH:45][c:46]([S:47][c:48]2[cH:49][c:50]([C:51]#[C:52][c:53]3[cH:54][cH:55][c:56]([CH2:57][OH:58])[cH:59][cH:60]3)[cH:61][c:62]([O:63][CH2:64][CH2:65][c:66]3[cH:67][cH:68][c:69]([Cl:70])[cH:71][cH:72]3)[cH:73]2)[cH:74][c:75]1[CH3:76])[CH3:77]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][O:6][c:7]1[c:8]([CH3:26])[cH:9][c:10]([S:13][c:14]2[cH:15][c:16]([C:30]#[C:29][CH2:28][N:31]3[CH2:32][CH2:33][O:34][CH2:35][CH2:36]3)[cH:17][c:18]([O:20][CH2:21][CH:22]3[CH2:23][CH2:24]3)[cH:19]2)[cH:11][cH:12]1)=[O:27]

Participants

4

Reactant 3

HCID 4129414-(2-Propyn-1-yl)morpholineHCID 58368330[4-(3-Bromo-5-cyclopropylmethoxy-phenylsulfanyl)-2-methyl-phenoxy]-acetic Acid ethyl esterHCID 67024299{4-[3-[2-(4-Chloro-phenyl)-ethoxy]-5-(4-hydroxymethyl-phenylethynyl)-phenylsulfanyl]-2-methylphenoxy}-acetic acid ethyl ester

Product 1

HCID 67169962{4-[3-Cyclopropylmethoxy-5-(3-morpholin-4-yl-prop-1-ynyl)-phenylsulfanyl]-2-methyl-phenoxy}-acetic Acid Ethyl Ester

Sources & evidence

ORD record
ord-5e71885450ab40e1bc5cc04a20c358c3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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