Diethyl Ether → 8-(1,3-Thiazol-2-yl)-1,4-dioxaspiro[4.5]decan-8-ol
Reaction equation
[Br:6][c:7]1[s:8][cH:9][cH:10][n:11]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH3:23][CH2:24][O:25][CH2:26][CH3:27].[O:12]1[CH2:13][CH2:14][O:15][C:16]12[CH2:17][CH2:18][C:19](=[O:22])[CH2:20][CH2:21]2>>[c:7]1([C:19]2([OH:22])[CH2:18][CH2:17][C:16]3([O:12][CH2:13][CH2:14][O:15]3)[CH2:21][CH2:20]2)[s:8][cH:9][cH:10][n:11]1Participants
5
Sources & evidence
- ORD record
- ord-3eacdcf485df4f189c9a7cdc79f65833
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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