1-Benzylazepan-3-one → 1-Benzyl-4-bromo-azepan-3-one

HRID 12065Notes

Reaction equation

HRID 12065 reaction equation
[CH2:1]([N:8]1[CH2:14][CH2:13][CH2:12][CH2:11][C:10](=[O:15])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:16]C1CC(C(C)C)CCC1=O>>[CH2:1]([N:8]1[CH2:14][CH2:13][CH2:12][CH:11]([Br:16])[C:10](=[O:15])[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 151522641-Benzylazepan-3-oneHCID 627080672-Bromo-4-isopropyl-cyclohexanone

Product 1

HCID 686817601-Benzyl-4-bromo-azepan-3-one

Procedure

The bromination of 1-benzyl-azepan-3-one takes place in a manner similar to that described above for the preparation of 2-bromo-4-isopropyl-cyclohexanone. The title compound is reacted as a crude product without further characterization.

Sources & evidence

ORD record
ord-e2c1f42674774ba8814ec0d8b095ea7e
Source dataset
uspto-grants-2010_06
Patent number
US07727979B2

Reaction notes

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