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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1206500Generated: October 26, 2026

Bicarbonate Ion → N-(4-(2-((t-butyl(dimethyl)silyl)oxy)-4-hydroxybutanoyl)-3-fluorophenyl)pyridine-2-carboxamide

https://huagongshe.com/reaction/1206500

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantTetrahydrofuranHCID 8028—
Reactant3-(tert-butyldimethylsilyloxy)dihydrofuran-2(3H)-oneHCID 5046241—
ReactantN-(4-bromo-3-fluorophenyl)pyridine-2-carboxamideHCID 23145244—
ReactantButyllithiumHCID 178418339—
ProductN-(4-(2-((t-butyl(dimethyl)silyl)oxy)-4-hydroxybutanoyl)-3-fluorophenyl)pyridine-2-carboxamideHCID 67482856—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-75d5d43375324e648d59cae22852c185
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)