Citric Acid → Amantadine
Reaction equation
[C:23]([CH3:24])([CH3:25])([CH3:26])[O:27][C:28]([CH2:29][CH:30]([C:31](=[O:32])[OH:33])[P:34]([O:35][CH2:36][CH3:37])([O:38][CH2:39][CH3:40])=[O:41])=[O:42].[C:62]12([NH2:72])[CH2:63][CH:64]3[CH2:65][CH:66]([CH2:67][CH:68]([CH2:69]1)[CH2:70]3)[CH2:71]2.[CH3:43][C:44]([CH3:45])([O-:46])[CH3:47].[CH3:74][c:75]1[cH:76][cH:77][cH:78][cH:79][cH:80]1.[Na+:22].[Na+:48].[OH2:73].[OH:1][CH:2]([CH2:3][CH2:4][c:5]1[cH:6][c:7]([CH3:17])[c:8](-[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[cH:9][cH:10]1)[S:18]([O-:19])(=[O:20])=[O:21].[OH:49][C:50]([CH2:51][C:52]([C:53](=[O:54])[OH:55])([CH2:56][C:57](=[O:58])[OH:59])[OH:60])=[O:61]>>[C:62]12([NH2:72])[CH2:63][CH:64]3[CH2:65][CH:66]([CH2:67][CH:68]([CH2:69]1)[CH2:70]3)[CH2:71]2.[CH:2]([CH2:3][CH2:4][c:5]1[cH:6][c:7]([CH3:17])[c:8](-[c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[cH:9][cH:10]1)=[C:30]([CH2:29][C:28]([O:27][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:42])[C:31](=[O:32])[OH:33]Participants
10
Reactant 8
Product 2
Sources & evidence
- ORD record
- ord-c9e87725ab2642a6af19d37fcc2c3265
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…