tert-Butyl 1-(4-(8-(2-hydroxyethoxy)-4-oxo-2-phenyl-4H-pyrano[2,3-c]pyridin-3-yl)phenyl)cyclobutylcarbamate → 3-(4-(1-aminocyclobutyl)phenyl)-8-(2-hydroxyethoxy)-2-phenyl-4H-pyrano[2,3-c]pyridin-4-one
Reaction equation
[NH2:1][C:2]1([c:3]2[cH:4][cH:5][c:6](-[c:7]3[c:8](=[O:9])[c:10]4[c:11]([o:12][c:13]3-[c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[c:20](-[c:21]3[c:22]([CH3:23])[n:24][n:25]([CH3:26])[c:27]3[CH3:28])[n:29][cH:30][cH:31]4)[cH:32][cH:33]2)[CH2:34][CH2:35][CH2:36]1.[OH:37][CH2:38][CH2:39][O:40][c:41]1[n:42][cH:43][cH:44][c:45]2[c:46]1[o:47][c:48](-[c:70]1[cH:71][cH:72][cH:73][cH:74][cH:75]1)[c:49](-[c:52]1[cH:53][cH:54][c:55]([C:58]3([NH:62][C:63](=[O:64])[O:65][C:66]([CH3:67])([CH3:68])[CH3:69])[CH2:59][CH2:60][CH2:61]3)[cH:56][cH:57]1)[c:50]2=[O:51]>>[OH:37][CH2:38][CH2:39][O:40][c:41]1[n:42][cH:43][cH:44][c:45]2[c:46]1[o:47][c:48](-[c:70]1[cH:71][cH:72][cH:73][cH:74][cH:75]1)[c:49](-[c:52]1[cH:53][cH:54][c:55]([C:58]3([NH2:62])[CH2:59][CH2:60][CH2:61]3)[cH:56][cH:57]1)[c:50]2=[O:51]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-74c8fb21d40f446e95f4f1c65aeeefcd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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