Methanol → 5-[2-Fluoro-4-(methylsulfonyl)phenyl]-2-pyrazinamine
Reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[CH2:32]1[O:33][CH2:34][CH2:35][O:36][CH2:37]1.[CH3:38][OH:39].[Cl:29][CH2:30][Cl:31].[F:9][c:10]1[c:11]([B:20]([OH:21])[OH:22])[cH:12][cH:13][c:14]([S:16](=[O:17])(=[O:18])[CH3:19])[cH:15]1.[NH2:1][c:2]1[n:3][cH:4][c:5]([Br:8])[n:6][cH:7]1.[Na+:27].[Na+:28].[cH:40]1[cH:41][cH:42][c:43]([P:44]([Pd:45]([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)([P:65]([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[P:84]([c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)([c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)[cH:115][cH:116]1>>[NH2:1][c:2]1[n:3][cH:4][c:5](-[c:11]2[c:10]([F:9])[cH:15][c:14]([S:16](=[O:17])(=[O:18])[CH3:19])[cH:13][cH:12]2)[n:6][cH:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-5877c2de873b4d7db8fcd7dfe81a6ae2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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