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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1207103Generated: October 26, 2026

Tetrahydrofuran → 3-(2,6-Dichloro-4-methoxy-benzyl)-1-(1,4-dioxa-spiro[4.5]dec-8-yl)-pyrrolidin-2-one

https://huagongshe.com/reaction/1207103

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantDiisopropylamideHCID 5062348—
Reactant1-(1,4-Dioxaspiro[4.5]decan-8-yl)pyrrolidin-2-oneHCID 10900293—
Reactant2-(Bromomethyl)-1,3-dichloro-5-methoxybenzeneHCID 59299479—
Product3-(2,6-Dichloro-4-methoxy-benzyl)-1-(1,4-dioxa-spiro[4.5]dec-8-yl)-pyrrolidin-2-oneHCID 57878599—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (5/10)
ORD IDord-f1b88c6cd2e049f09eaf68331d7e5b55
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (5/10)