Methyl 3-(chloromethyl)-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate → methyl 1-(3-chloropyridin-2-yl)-5-hydroxy-3-(hydroxymethyl)-4,5-dihydro-1H-pyrazole-5-carboxylate
Reaction equation
[Cl:1][c:2]1[c:3]([N:8]2[N:9]=[C:10]([CH2:19][OH:20])[CH2:11][C:12]2([C:13](=[O:14])[O:15][CH2:16][CH3:17])[OH:18])[n:4][cH:5][cH:6][cH:7]1.[Cl:21][c:22]1[c:23](-[n:24]2[c:25]([C:26]([O:27][CH3:28])=[O:29])[cH:30][c:31]([CH2:32][O:33][S:34]([CH3:35])(=[O:36])=[O:37])[n:38]2)[n:39][cH:40][cH:41][cH:42]1.[Cl:43][CH2:44][c:45]1[cH:46][c:47]([C:48]([O:49][CH3:50])=[O:51])[n:52](-[c:53]2[c:54]([Cl:55])[cH:56][cH:57][cH:58][n:59]2)[n:60]1>>[Cl:1][c:2]1[c:3]([N:8]2[N:9]=[C:10]([CH2:19][OH:20])[CH2:11][C:12]2([C:13](=[O:14])[O:15][CH3:16])[OH:18])[n:4][cH:5][cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-8c28e74539924fff81eaab9ed9a06a34
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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