(6-Fluoro-5-methylpyridin-3-yl)boronic acid → [7-(6-Fluoro-5-methyl-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine

HRID 1207286Notes

Reaction equation

HRID 1207286 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][n:7][c:8]([NH:11][c:12]3[cH:13][cH:14][c:15]([N:18]4[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]4)[cH:16][cH:17]3)[n:9][n:10]12.[F:25][c:26]1[n:27][cH:28][c:29]([B:33]([OH:34])[OH:35])[cH:30][c:31]1[CH3:32]>>[c:2]1(-[c:29]2[cH:28][n:27][c:26]([F:25])[c:31]([CH3:32])[cH:30]2)[cH:3][cH:4][c:5]2[cH:6][n:7][c:8]([NH:11][c:12]3[cH:13][cH:14][c:15]([N:18]4[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]4)[cH:16][cH:17]3)[n:9][n:10]12

Participants

3

Reactant 2

HCID 17750247(6-Fluoro-5-methylpyridin-3-yl)boronic acidHCID 66711200(7-Bromo-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine

Product 1

HCID 66711923[7-(6-Fluoro-5-methyl-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-[4-(4-methyl-piperazin-1-yl)-phenyl]-amine

Sources & evidence

ORD record
ord-8b97d44903ca4147b03e492f06978c40
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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