Dichloromethane → 1-(4-(methylthio)phenyl)-4-(piperidin-4-yloxy)pyridin-2(1H)-one

HRID 1207353Notes

Reaction equation

HRID 1207353 reaction equation
[CH3:1][S:2][c:3]1[cH:4][cH:5][c:6](-[n:9]2[c:10](=[O:32])[cH:11][c:12]([O:15][CH:16]3[CH2:17][CH2:18][N:19]([C:22]([O:23][CH2:24][c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)=[O:31])[CH2:20][CH2:21]3)[cH:13][cH:14]2)[cH:7][cH:8]1.[Cl:38][CH2:39][Cl:40].[I:33][Si:34]([CH3:35])([CH3:36])[CH3:37]>>[CH3:1][S:2][c:3]1[cH:4][cH:5][c:6](-[n:9]2[c:10](=[O:32])[cH:11][c:12]([O:15][CH:16]3[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]3)[cH:13][cH:14]2)[cH:7][cH:8]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 85247Trimethylsilyl iodideHCID 67368480Benzyl 4-(1-(4-(methylthio)phenyl)-2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate

Product 1

HCID 673687081-(4-(methylthio)phenyl)-4-(piperidin-4-yloxy)pyridin-2(1H)-one

Sources & evidence

ORD record
ord-6a39d41b182c48f5ba11e4d3521d0ccf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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