tert-Butyl piperazine-1-carboxylate → 4-(4-Cyano-2,3-difluoro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[F:14][c:15]1[c:16]([C:17]#[N:18])[cH:19][cH:20][c:21]([F:24])[c:22]1[F:23]>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][N:11]([c:21]2[cH:20][cH:19][c:16]([C:17]#[N:18])[c:15]([F:14])[c:22]2[F:23])[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-e1e28bbce1d0473ea8d46deae7d24a8d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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