1-(2-Hydroxyethyl)piperazine → HCID 10460847, compound

HRID 1207675Notes

Reaction equation

HRID 1207675 reaction equation
[NH2:1][c:2]1[n:3][c:4]([NH:19][CH:20]2[CH2:21][CH2:22][N:23]([S:26](=[O:27])(=[O:28])[CH2:29][CH2:30][CH2:31][Cl:32])[CH2:24][CH2:25]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:17][CH3:18])[cH:12][cH:13][c:14]([F:16])[cH:15]1.[OH:33][CH2:34][CH2:35][N:36]1[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]1>>[NH2:1][c:2]1[n:3][c:4]([NH:19][CH:20]2[CH2:21][CH2:22][N:23]([S:26](=[O:27])(=[O:28])[CH2:29][CH2:30][CH2:31][N:39]3[CH2:38][CH2:37][N:36]([CH2:35][CH2:34][OH:33])[CH2:41][CH2:40]3)[CH2:24][CH2:25]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:17][CH3:18])[cH:12][cH:13][c:14]([F:16])[cH:15]1

Participants

3

Reactant 2

HCID 76771-(2-Hydroxyethyl)piperazineHCID 10458099[4-Amino-2-[1-(3-chloro-propane-1-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone

Product 1

HCID 10460847HCID 10460847, compound

Sources & evidence

ORD record
ord-d081b6329cf94fa1a557c1e362486924
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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