Acetic Acid → 5,6-Dihydromidazolam

HRID 1207683Notes

Reaction equation

HRID 1207683 reaction equation
[CH2:24]([Cl:25])[Cl:26].[CH3:27][C:28](=[O:29])[OH:30].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:23]1)[C:7]([c:16]1[c:17]([F:22])[cH:18][cH:19][cH:20][cH:21]1)=[N:8][CH2:9][c:10]1[n:11]-2[c:12]([CH3:15])[n:13][cH:14]1.[Zn:31]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:23]1)[CH:7]([c:16]1[c:17]([F:22])[cH:18][cH:19][cH:20][cH:21]1)[NH:8][CH2:9][c:10]1[n:11]-2[c:12]([CH3:15])[n:13][cH:14]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 4192MidazolamHCID 6344DichloromethaneHCID 23994Zinc

Product 1

HCID 99019425,6-Dihydromidazolam

Sources & evidence

ORD record
ord-69613cf1b3434b07aa60cd982252f581
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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