2-(1-tert-Butoxycarbonylpiperidin-4-yloxy)-4-(methylthio)benzoic acid → n-(5-Chloropyridin-2-yl)-4-iodo-2-[4-methylthio-2-(1-t-butoxycarbonylpiperidin-4-yloxy)benzoylamino]benzamide

HRID 1207792Notes

Reaction equation

HRID 1207792 reaction equation
[CH3:19][S:20][c:21]1[cH:22][c:23]([O:30][CH:31]2[CH2:32][CH2:33][N:34]([C:37](=[O:38])[O:39][C:40]([CH3:41])([CH3:42])[CH3:43])[CH2:35][CH2:36]2)[c:24]([C:25](=[O:26])[OH:27])[cH:28][cH:29]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([NH2:17])[cH:12][c:13]([I:16])[cH:14][cH:15]2)=[O:18])[n:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([NH:17][C:25]([c:24]3[c:23]([O:30][CH:31]4[CH2:32][CH2:33][N:34]([C:37](=[O:38])[O:39][C:40]([CH3:41])([CH3:42])[CH3:43])[CH2:35][CH2:36]4)[cH:22][c:21]([S:20][CH3:19])[cH:29][cH:28]3)=[O:26])[cH:12][c:13]([I:16])[cH:14][cH:15]2)=[O:18])[n:6][cH:7]1

Participants

3

Reactant 2

HCID 115596842-(1-tert-Butoxycarbonylpiperidin-4-yloxy)-4-(methylthio)benzoic acidHCID 68535003N-(5-chloropyridin-2-yl)-4-iodo-2-aminobenzamide

Product 1

HCID 68533929n-(5-Chloropyridin-2-yl)-4-iodo-2-[4-methylthio-2-(1-t-butoxycarbonylpiperidin-4-yloxy)benzoylamino]benzamide

Sources & evidence

ORD record
ord-644ed33ad5bd40a7ae50a9f8c8280c4e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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