4-Chloro-2-fluorobenzoic acid → (8-Chloro-1-methyl-1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-ylidenemethyl)phosphonic acid diethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][P:4]([O:5][CH2:6][CH3:7])(=[O:8])[CH:9]=[C:10]1[c:11]2[c:12]([cH:18][cH:19][cH:20][cH:21]2)[N:13]([CH3:17])[CH2:14][CH2:15][NH:16]1.[Cl:22][c:23]1[cH:24][cH:25][c:26]([C:27]([OH:28])=[O:29])[c:30]([F:31])[cH:32]1>>[CH2:1]([CH3:2])[O:3][P:4]([O:5][CH2:6][CH3:7])(=[O:8])[CH:9]=[C:10]1[c:11]2[c:12]([cH:18][c:19]([Cl:22])[cH:20][cH:21]2)[N:13]([CH3:17])[CH2:14][CH2:15][NH:16]1Participants
3
Sources & evidence
- ORD record
- ord-b4872455deb04b2a83354d42ff89006f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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