Carbonate Ion → 7-(5-Fluoro-3-methylpyridin-2-yl)-N-(5-(trifluoromethyl)pyrimidin-2-yl)-1,8-naphthyridin-4-amine
Reaction equation
[C:31](=[O:32])([O-:33])[O-:34].[Cl:1][c:2]1[c:3]2[cH:4][cH:5][c:6](-[c:12]3[n:13][cH:14][c:15]([F:19])[cH:16][c:17]3[CH3:18])[n:7][c:8]2[n:9][cH:10][cH:11]1.[Cs+:35].[Cs+:36].[NH2:20][c:21]1[n:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][n:26]1.[O:37]1[CH2:38][CH2:39][O:40][CH2:41][CH2:42]1.[O:45]=[C:46]([CH:47]=[CH:48][c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1)[CH:55]=[CH:56][c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1.[O:63]=[C:64]([CH:65]=[CH:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1)[CH:73]=[CH:74][c:75]1[cH:76][cH:77][cH:78][cH:79][cH:80]1.[O:81]=[C:82]([CH:83]=[CH:84][c:85]1[cH:86][cH:87][cH:88][cH:89][cH:90]1)[CH:91]=[CH:92][c:93]1[cH:94][cH:95][cH:96][cH:97][cH:98]1.[Pd:43].[Pd:44]>>[c:2]1([NH:20][c:21]2[n:22][cH:23][c:24]([C:27]([F:28])([F:29])[F:30])[cH:25][n:26]2)[c:3]2[cH:4][cH:5][c:6](-[c:12]3[n:13][cH:14][c:15]([F:19])[cH:16][c:17]3[CH3:18])[n:7][c:8]2[n:9][cH:10][cH:11]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-eba7c75331a84cfe99dd165dd8175b9b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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