Ammonia → 5-[6-({[tert-butyl(dimethyl)silyl]oxy}methyl)-1H-imidazo[4,5-c]pyridin-1-yl]-3-{1-[2-(trifluoromethyl)phenyl]ethoxy}thiophene-2-carboxamide
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[n:14][cH:15][n:16]2-[c:17]1[cH:18][c:19]([O:26][CH:27]([CH3:28])[c:29]2[c:30]([C:35]([F:36])([F:37])[F:38])[cH:31][cH:32][cH:33][cH:34]2)[c:20]([C:22]([O:24][CH3:23])=[O:25])[s:21]1)([CH3:39])[CH3:40].[CH3:42][OH:43].[NH3:41]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][c:8]1[cH:9][c:10]2[c:11]([cH:12][n:13]1)[n:14][cH:15][n:16]2-[c:17]1[cH:18][c:19]([O:26][CH:27]([CH3:28])[c:29]2[c:30]([C:35]([F:36])([F:37])[F:38])[cH:31][cH:32][cH:33][cH:34]2)[c:20]([C:22](=[O:24])[NH2:41])[s:21]1)([CH3:39])[CH3:40]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-ce2a4240538a4dd48477394216870280
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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