5-(2,4-dichlorophenyl)-N-(2-ethoxy-2,3-dihydro-1H-inden-1-yl)-3,6-diethylpyrazin-2-amine → 5-[6-(dimethylamino)-4-methyl-3-pyridinyl]-N-(2-ethoxy-2,3-dihydro-1H-inden-1-yl)-3,6-diethylpyrazin-2-amine

HRID 120817Notes

Reaction equation

HRID 120817 reaction equation
[CH3:32][N:33]([c:34]1[cH:35][c:36]([CH3:61])[c:37](-[c:40]2[n:41][c:42]([CH2:59][CH3:60])[c:43]([NH:48][CH:49]3[c:50]4[c:51]([cH:52][cH:53][cH:54][cH:55]4)[CH2:56][CH:57]3[OH:58])[n:44][c:45]2[CH2:46][CH3:47])[cH:38][n:39]1)[CH3:62].[Cl:1][c:2]1[cH:3][c:4]([Cl:5])[cH:6][cH:7][c:8]1-[c:9]1[n:10][c:11]([CH2:12][CH3:13])[c:14]([NH:15][CH:18]2[CH:19]([O:27][CH2:28][CH3:29])[CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][c:26]32)[n:16][c:17]1[CH2:30][CH3:31]>>[CH:18]1([NH:48][c:43]2[c:42]([CH2:59][CH3:60])[n:41][c:40](-[c:37]3[c:36]([CH3:61])[cH:35][c:34]([N:33]([CH3:32])[CH3:62])[n:39][cH:38]3)[c:45]([CH2:46][CH3:47])[n:44]2)[CH:19]([O:27][CH2:28][CH3:29])[CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][c:26]21

Participants

3

Reactant 2

HCID 221473105-(2,4-dichlorophenyl)-N-(2-ethoxy-2,3-dihydro-1H-inden-1-yl)-3,6-diethylpyrazin-2-amineHCID 22147422HCID 22147422, compound

Product 1

HCID 221473405-[6-(dimethylamino)-4-methyl-3-pyridinyl]-N-(2-ethoxy-2,3-dihydro-1H-inden-1-yl)-3,6-diethylpyrazin-2-amine

Sources & evidence

ORD record
ord-715a4c90f1ab4f56b98b9087f8c5bc99
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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